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PhD studentship – FTIR, Raman and SIMS Imaging for Lipidomic Analysis

PhD studentship – FTIR, Raman and SIMS Imaging for Lipidomic Analysis

FTIR, Raman and SIMS Imaging for Lipidomic Analysis of Cellular Systems Prof P Gardner, Dr N Lockyer, Dr J Denbigh Deadline 17 November 2017 The role of lipid metabolism in a number of cellular processes including (i) stem cell differentiation, (ii) drugcell interactions and (iii) epithelial/adipocyte cell interactions, is generally poorly understood. For example it has been recently shown that PC3 cells when co-cultured with adipocyte cells, sequestrate omega-6 lipids and their metabolites which subsequently stimulate cell migration and whilst…

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PhD studentship – Secondary effects of gene mutations

PhD studentship – Secondary effects of gene mutations

Probing the secondary effects of Tp53 and BRCA gene mutations upon cellular physiology using advanced analytical techniques. Prof R Edmondson, Prof P Gardner, Dr N Lockyer, Dr J Denbigh Deadline: 17 November 2017 Cancer is a disease of DNA in which genomic events allow the cell to develop the autonomy, increased proliferation and other fundamental hallmarks of the disease. This process is often initiated by mutation of one or two key driver genes. Understanding the effects of these driver mutations…

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